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diagnosis biliary cholangitis cirrhosis gap globulin injury lfts liverenzymes lupus pbc primary protein proteingap rheumatology sle systemic workup
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... #hepatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Noninfectious hepatitis ... Cytopenias • Cardiac valve ... , Serositis Labs ... common • Antihistone
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Female:Male 9:1 • Common ... intralobular bile ducts causes ... wasting PBC Labs ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
HBV, EBV, VZV, hepatitis ... ETOH, autoimmune hepatitis ... PBC, PSC, Viral hepatitis ... gastric tumors • Hematology ... #diagnosis #hematology
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