4 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... and hepatitis ... levels are within normal ... DDX - Other causes ... #hematology #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
hepatitis C) • ... ETOH, autoimmune hepatitis ... PBC, PSC, Viral hepatitis ... gastric tumors • Hematology ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... Noninfectious hepatitis ... , Serositis Labs ... common • Antihistone ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... vasculitis: 10%-16% Liver ... • Autoimmune hepatitis ... #Syndrome #Rheumatology