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acute aplastic erythematosus gap globulin hiv hypogammaglobulinemia immunodeficiency injury lupus oncology protein proteingap sjogrens sle systemic variable
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... and hepatitis ... levels are within normal ... DDX - Other causes ... #hematology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... Chronic viral hepatitis ... #injury #hepatitis ... diagnosis #algorithm ... #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... : - Hepatitis ... Treatment: ... #oncology #hematology ... #diagnosis #management
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Retroviral Syndrome ... infection - Most common ... manifestations Labs ... enzymes ↑ • Mild anemia ... infection • Viral hepatitis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
HBV, EBV, VZV, hepatitis ... ETOH, autoimmune hepatitis ... PBC, PSC, Viral hepatitis ... gastric tumors • Hematology ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Noninfectious hepatitis ... Cytopenias • Cardiac valve ... common • Antihistone ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... vasculitis: 10%-16% Liver ... • Autoimmune hepatitis ... #Rheumatology # ... Diagnosis #Management
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