15 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Wilsons, Pregnancy - AFLP ... AST): • US - Normal ... LFTs #Elevated #Abnormal ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... disease US — Normal ... hepatitis • Drugs ... Others #LFTs #Hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Infectious • Hepatitis ... Hepatitis • Autoimmune ... Hepatitis • Drug ... Induced Hepatitis ... #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... Hepatitis, TPN ... Sepsis, Viral Hepatitis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- If both are normal ... function may be abnormal ... Chronic viral hepatitis ... #injury #hepatitis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... - If both are normal ... • Near normal ... #differential #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Hepatic imaging: Normal ... • Histology: Normal-mild ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
wasting PBC Labs ... • ALT & AST normal ... • Bilirubin - Normal ... : • Viral hepatitis ... #workup #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... *Abnormal USS may ... #LFTs #Abnormal ... #Algorithm #Hepatology