9 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Idiopathic • Normal ... ANCA (C-ANCA): GPA ... eGPA, MPA >>> GPA ... #diagnosis #algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Decreased Support Of Dermal ... vasculitis - GPA ... #Diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... RA, Sjogren's, GPA ... deficiency Work ... #Causes #dermatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... , but normal values ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... blood cells appear normal ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Oral / Mouth Lesions and Ulcers (Adult & Elderly) - Differential Diagnosis Algorithm

Teeth
 • GERD (Dissolves
Adult & Elderly) - Differential ... Diagnosis Algorithm ... Cold Sore • Anemia ... polyangiitis (GPA ... #Causes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Thalassemia, Sickle cell anemia ... light chain • Normal ... #ProteinGap #differential ... #diagnosis #hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... • Normocytic anemia ... generally are normal ... and can help differentiate ... TREATMENT: • The
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
products that define normal ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology