15 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... disease US — Normal ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... Elevated ALP 2. ... #Biliary #Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... • ALT & AST normal ... or slightly elevated ... • Bilirubin - Normal ... diagnosis #workup #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
of Anemia with elevated ... Differential Diagnosis Algorithm ... Neutrophils - Low RBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... - If both are normal ... hepatitis: < 1 • Cirrhosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... specificity to elevated ... - If both are normal ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... Patients with cirrhosis ... hemochromatosis #algorithm ... diagnosis #management #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... > 5 or elevated ... 500 mg QD until normal ... diagnosis #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... protein C and S Pathophysiology ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... treatment #management #hematology