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management infections infectiousdiseases pulmonary amiodarone cvid differential erythematosus fungal hematology hiv hypogammaglobulinemia immunodeficiency immunology induced lupus mycoses sjogrens sle syndrome
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential Diagnosis ... consolidation or nodular ... Exam: Can be normal ... Infections #HIV #AIDS ... #differential #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... community-acquired infections: Pneumonia ... levels are within normal
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... , ARDS, DAH, solitary ... • Reticular + Nodular ... Eosinophilia • Normal
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... sedimentation rate + Normal ... Differential Diagnosis ... Kidney disease common ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... salivary ducts Clinical ... Usual interstitial pneumonia ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
droppings • Most common ... pulmonary symptoms • Rheumatologic ... yeast • At risk: AIDS ... level • A low or normal ... osteoarticular, pulmonary, ocular
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