13 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... - CRP: Usually normal ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... - CRP: Usually normal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... #management #treatment
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
study (aPTT may be normal ... in mild cases) ... antigen (vWF:Ag) are normal ... Avoid meds that ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
it should not cause ... dissociative drug, it causes ... including HTN), and ↑ oral ... Delirium #PAD #ICU #CriticalCare ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE ... #management #neurology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... sx overlap with normal ... orthopnea, PND, LE ... teratogenic GDMT meds
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
hypertension 3) Abnormal ... anemia (MAHA) Pathophysiology ... , add other BP meds ... • Refractory cases ... Renal #Crisis #rheumatology