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algorithm ascites causes lfts liver abnormal gradient saag transaminitis workup chemistry cholangitis elevated enzymes fatty gap globulin hematology hepatomegaly hypertension
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... congenital - Primary biliary ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
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 Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Wilsons, Pregnancy - AFLP ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... #hepatology #LiverFunctionTests
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic ... or chronic hepatitis ... Failure, Pancreatic, Biliary ... #Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... #Causes #Hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome SAAG < 1.1: Biliary ... #gradient #hepatology ... #differential #
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... INR, bilirubin, albumin ... /acute hepatitis ... pregnancy • Primary biliary ... #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Diagnosis High ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... Tuberculosis - Biliary ... #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Production: • Albumin ... : < 1 • Cirrhosis ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... : < 1 • Cirrhosis ... #differential # ... #hepatology
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