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diagnosis causes algorithm lfts liver pbc ascites chemistry cholangitis gradient hepatomegaly hypertension injury interpretation liverenzymes management portal rvalue saag serum
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Malignant • Primary ... Biliary Cirrhosis ... #Hepatomegaly #Differential ... Algorithm #Causes #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... congenital - Primary ... biliary cirrhosis ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
INR, bilirubin, albumin ... /acute hepatitis ... pregnancy • Primary ... biliary cirrhosis ... Diagnosis #causes #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Production: • Albumin ... • Near normal ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Extrahepatic - Biliary ... : < 1 • Cirrhosis ... #differential # ... diagnosis #algorithm #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) - Differential ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... Tuberculosis - Biliary ... #Diagnosis #hepatology
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... line therapy if ALP ... complex: Artificial tears ... #Biliary #Cirrhosis ... Management #Treatment #hepatology
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