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diagnosis algorithm causes lfts liver abnormal ascites management pbc primary transaminitis albumin chemistry cholangitis elevated enzymes fatty gradient hepatomegaly hypertension
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... congenital - Primary biliary ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Wilsons, Pregnancy - AFLP ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... Algorithm #diagnosis #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... liver disease (cirrhosis ... or chronic hepatitis ... Failure, Pancreatic, Biliary ... #Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... #Differential # ... Algorithm #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Extrahepatic - Biliary ... : < 1 • Cirrhosis ... #differential # ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... obstruction • ALP ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... • Near normal ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... /acute hepatitis ... pregnancy • Primary biliary ... #Hypertension #Differential ... Diagnosis #causes #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
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