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liver algorithm pregnancy abnormal biliary chemistry cholangitis cirrhosis classification comparison disease enzymes fatty hellp icp injury interpretation liverenzymes management obgyn
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... infiltration) Differential ... Hepatitis, Preeclampsia ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... • Near normal ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... #differential # ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... mellitus; USS, ultrasound ... #LFTs #Abnormal ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... tract, and often causes ... well as inner ear ... Tests: • CBC • LFT
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