15 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
of Severe Acute Liver ... - Acute biliary ... - Wilson disease ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... PSC - Other biliary ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Extrahepatic - Biliary ... - Obstruction: Biliary ... #differential # ... diagnosis #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... , Acute biliary ... Extrahepatic • Biliary ... #Injury #Differential ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Cholestatic disease ... • Alcoholic hepatitis ... Duct Stone • Biliary
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... congenital - Primary biliary ... Nonalcoholic fatty liver ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Cholangitis • Primary Biliary ... Algorithm #Causes #Hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... or chronic hepatitis ... Failure, Pancreatic, Biliary ... #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... • Near normal ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... of Pregnancy (AFLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #