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diagnosis liver algorithm lfts obstetrics pregnancy causes chemistry comparison disease fatty injury interpretation liverenzymes management obgyn pathophysiology rvalue transaminitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
of Pregnancy (ICP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • Pregnancy - AFLP ... , HELLP Moderate ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... • Near normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... • Pregnancy: HELLP ... Chronic viral hepatitis ... #differential # ... diagnosis #algorithm #hepatology
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