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diagnosis anemia aplastic cmv covid19 cytomegalovirus differential hematology hivaids idsa inflammatory oncology opportunistic prevention reconstitution siltuximab syndrome tocilizumab treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... increase in CD4+ cells ... with severe symptoms ... weeks for most OI ... Differential #Diagnosis #Management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19 IL-6 activates T cells and macrophages, among other cell types (see
-6 activates T cells ... respiratory tract infection ... anti-IL6 mAb) #AntiIL6 ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... - Antithyroid medications ... HCV - HIV • Immune ... • Improve the symptoms ... hematology #diagnosis #management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
CD4 count >100 cells ... ., concomitant medications ... contralateral eye ... Prevention #Treatment #management ... #HIVAIDS #pharmacology
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