4 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... cells -> Mutagenic ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... EMG: LMN Signs in ... neurology #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... #diagnosis #management ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... mediators such as ... #Signs #Symptoms