9 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... signs and symptoms ... Low or absent NK cell ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
is identical to ... with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... workup #oncology #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: Inflammatory eye ... Genital ulcers • Eye ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) is an uncommon ... accounts for 10% of all ... ingestion • B symptoms ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry eyes ... neuropathy, transverse myelitis ... Nephrogenic DI Hematologic ... #Rheumatology # ... Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Presentation - Systemic Symptoms ... Arthralgias • Eye ... purpura: strong sign ... Eye -> retinopathy ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
overgrowth of cells ... and the systemic symptoms ... mature plasma cells ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Males • Affects all ... ethnicities Symptoms ... vessels (aorta) • Eyes ... Polychondritis #rheumatology ... #diagnosis #management