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diagnosis hematology differential neurology rheumatology oncology als amyotrophic anemia aplastic chronic cll disease hemeonc hemophagocytic hlh inflammatory leukemia leukostasis lymphocytic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #IRIS #Immune ... Differential #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Genital ulcers • Eye ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... • Improve the symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Microglial cells ... are the immune ... cells of the nervous ... diagnosis column Treatment ... between nerve cells
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... ophthalmoplegia), systemic signs ... tears oint + TAPE eye ... within 4m #Bells ... #Treatment #Neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... Physical Exam/Signs ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... activity → local immune ... tissue: Epithelioid cells ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... Multinucleated giant cells ... • Progressive symptoms ... vasculitis • Behcet
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... signs and/or symptoms ... Pleocytosis > 100 cells ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
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