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differential neurology rheumatology als amyotrophic bells disease hematology immune inflammatory leukostasis lysis myelitis palsy polychondritis reconstitution relapsing sarcoidosis sclerosis tls
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Genital ulcers • Eye ... Arthritis, AS Treatment ... #Syndrome #diagnosis ... #management #signs
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... #TLS #diagnosis ... #management #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... fasciculations Common Symptoms ... EMG: LMN Signs in ... column Treatment ... #management
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... tears oint + TAPE eye ... #Management #Treatment
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... tissue: Epithelioid cells ... at the time of diagnosis ... #Management #Signs
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Hyperreflexia develops later ... signs and/or symptoms ... Pleocytosis > 100 cells ... Transverse Myelitis Treatment ... #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... vasculitis • Behcet
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... vessels (aorta) • Eyes ... Sarcoidosis • Behcet ... affected tissue Treatment ... #management
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