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diagnosis treatment differential activetb latenttb neurology syndrome tb tuberculosis barre causes cystitis emphysematous fungal guillain guillainbarre hemophagocytic hlh infectiousdiseases inflammatory
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Pathophysiology ... Lung Abscess - Clinical ... 38 degrees • Chills
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... emboli • Lung abscess ... rest LTBI (-) Immune ... characteristic features Clinical ... TB #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... emboli • Lung abscess ... rest LTBI (-) Immune ... characteristic features Clinical ... TB #Diagnosis #Management
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
urinary catheter and immune ... compromise Clinical ... may have fever/chills ... present or signs of infection ... Pathophysiology:
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... : • Immune response ... preceding infection ... Oropharyngeal Weakness • Oculomotor ... Syndrome #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... activation of an immune ... mediated disease • Immune ... Transverse Myelitis - Clinical ... Myelitis #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... osteomyelitis, cutaneous abscesses ... Fever, chills, lack ... Differential #Diagnosis #Management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... activity → local immune ... renal failure Clinical ... anterior/posterior MSK
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... fungal stain of clinical ... Aspergillosis Pathophysiology ... Sinusitis • Brain abscess ... Fungal #Diagnosis #Management
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