9 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... • Secondary glaucoma ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
Central Retinal ... Occlusion #CRVO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Central Retinal ... (CRAO) • The retina ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle Glaucoma ... present with early glaucoma ... damage & blindness Signs ... #pathophysiology ... #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
nervefiber layer -> Retinal ... of the terminal retinal ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
from choroid to retina ... products from retina ... RPE -> Loss of photo ... MacularDegeneration #pathophysiology ... #ophthalmology
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
pathways occur at the retina ... activation of retina-driven ... meningeal irritation signs ... angle-closure glaucoma ... differential #diagnosis #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
influx and NO in retinal ... ganglion cells -> Retinal ... > Apoptosis of retinal ... #pathophysiology ... #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... influx and NO in retinal ... > Apoptosis of retinal ... #pathophysiology ... #ophthalmology