6 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... Transaminitis - Differential ... • Congenital: HELLP ... Trauma: Shock liver ... Metabolic: Wilson Disease
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Liver enzymes, ... hemorrhage Acute Fatty Liver ... features: Liver ... BrighamChiefs #Liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Pregnancy - AFLP, HELLP ... • Cholestatic disease ... • Alcoholic hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... • Pregnancy: HELLP ... specificity to elevated ... #injury #hepatitis ... #differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... develops (DIC, ascites ... Preeclampsia, HELLP ... Transfer to a liver
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver