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liver algorithm obstetrics pregnancy workup abnormal alkaline alp biliary chemistry cholangitis cirrhosis comparison disease disorders enzymes fatty hellp hematology hyophosphatasia
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis ... #LFTs #RValue #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... infiltration) Differential ... Hepatitis, Preeclampsia ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... #differential # ... #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... (CVID, WAS), (neurologic ... gastric bypass), LFT ... #Diagnosis #Causes ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... synthesized in: liver ... Most cases diagnosed ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... #Diagnosis #causes ... #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential # ... Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
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