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differential hepatology treatment causes hematology algorithm classification infectiousdiseases criticalcare gastroenterology hepatopulmonary hypertension infections nephrology portal signs ultrasound abdominal abnormal ascites
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
End Stage Liver ... Disease (Cirrhosis ... (HRS) • Liver ... SBP) #ESLD #Liver ... #diagnosis #management
Approach to the Hospitalized Patient with Cirrhosis 1) Recognize and Manage Decompensation • Ascites • Variceal Bleeding
Encephalopathy 2) ... • Hepatorenal Syndrome ... Portosystemic Shunt • Liver ... #diagnosis #treatment ... #management
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Failure (ACLF) Clinical ... disease, liver ... support, or liver ... #diagnosis
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Autoimmune (types 1, 2, ... Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... 14 percent) #Diagnosis
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 Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... and hepatorenal syndrome ... sarcoidosis) • Liver ... metastasis • Fatty liver
Causes of Portal Hypertension According to Site of Vascular Obstruction 1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
or secondary to cirrhosis ... including surgery 2) ... , Polycystic liver ... post-sinusoidal: Budd-Chiari syndrome ... #differential #diagnosis
Portal Hypertension Classification by site of vascular obstruction 1) Post-hepatic Post-sinusoidal: Budd-Chiari syndrome 2) Intrahepatic Post-sinusoidal: Veno-occlusive disease 3)
Post-sinusoidal: Budd-Chiari syndrome ... 2) Intrahepatic ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... gastroenterology #diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... HCV RNA • R 2- ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... #chemistry #diagnosis
Causes of Gallbladder Wall Thickening - Differential Diagnosis • Physiologic: Contracted gall bladder in a non-fasting
- Differential Diagnosis ... heart failure, Liver ... cirrhosis, Nephrotic ... syndrome, Pre-eclampsia ... #radiology #POCUS
Hepatorenal Syndrome Diagnosis • ↑ in serum Cr of ≥ 0.3mg/dL above baseline
Hepatorenal Syndrome ... Diagnosis • ↑ ... gradual • Severe liver ... (e.g. advanced cirrhosis ... #diagnosis #HRS
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