21 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Clinical Guidelines ... Brain Failure Lung ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... epidermis from dermis Clinical ... Signs/Symptoms/ ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... Inverse Gottron’s sign ... auricular papules Clinical ... anti-NXP2 Abs Lung ... #dermatology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... lymph node, or liver ... #management #treatment ... #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... >heart>liver>kidney ... symptoms, unexplained hematologic ... EBV viral load, signs ... #management #transplant
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Fraction (HFrEF) Clinical ... : weight gain, lung ... HFrEF may lack lung ... un lymphatic Diagnostic ... #management #cardiology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... disease • Liver ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
and Management ... absence of intrinsic lung ... shunt (Type 2) Clinical ... on radioactive lung ... #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... rash) • Heart, lung ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
causes (chronic lung ... m/s • Other signs ... Diagnostic criteria ... hemodynamics Liver ... #management #hepatology