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diagnosis differential aflp causes hematology hepatitis manifestations obstetrics pathophysiology pregnancy signs symptoms acidosis aclf activation aih autoimmune beriberi chronic cirrhosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... ACLF) Clinical Guidelines ... disease, liver ... #Hepatology #gastroenterology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
Clinical manifestations ... of acute liver ... abnormalities Liver ... Heart: High output ... #liver #failure
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... Transfer to a liver ... #AFLP #Fatty #Liver
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Findings in Hepatic / Liver ... —100-fold with acute ... liver failure; ... hepatocytes; in chronic liver ... has exhausted liver
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... Hemolysis, Elevated Liver ... Fatty Liver of ... features: Liver
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... including R heart failure ... • Cirrhosis/acute ... sarcoidosis) • Liver ... metastasis • Fatty liver
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
Framework and Clinical ... Beri: - High output ... Tachycardia - High output ... Findings: • Acute ... liver failure:
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... AIH #Diagnosis #Management ... #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
glucose by the liver ... contribution of liver ... - Low cardiac output ... mellitus/DKA - Liver ... gluconeogenesis Liver
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... of multiorgan failure ... lung, and kidney failure ... thrombocytopenia • Liver ... #Diagnosis #Management
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