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hematology management agglutinin cold cvid hodgkins immunodeficiency immunology leukemia lupus lymphocytic mds monoclonal myelodysplasia myelodysplastic paraproteinemias sle syndromes vasculitides workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... to impaired B-cell ... and autoimmune hemolytic ... anemia) • Systemic ... #immunology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
complements and a high ... Disease Classification ... common • Antihistone ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... #hemolytic #anemia ... #hematology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... Diagnosis: Systemic ... differential #diagnosis ... #rheumatology # ... classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... : Erythematous nodules ... #Differential #Diagnosis ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... - WBC may be high ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... MDS carries a variable ... Most common cytopenia ... #diagnosis #hematology ... #oncology
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