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hematology differential systemic algorithm leukemia secondary cll dermatologic erythematosus gpa granulomatosis lymphocytic management monoclonal paraproteinemias polyangiitis primary rash sle workup
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... Myelodisplastic syndrome ... #dermatology #Differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Pruritis ... nodosum • Immune hemolytic ... of cases) Classification ... #lymphoma #diagnosis ... #hematology #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... associated with pruritus ... • Goodpasture syndrome ... disease • Non-Hodgkin ... #rheumatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Skin Lesion - Differential ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... Myelodisplastic syndrome ... #causes
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell ... cyclophosphamide) • Hodgkin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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