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hematology classification cll erythematosus lupus lymphocytic management mds monoclonal myelodysplasia myelodysplastic paraproteinemias protein proteingap sle symptoms syndromes systemic vasculitides
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... globulin gap (> ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease) Differential ... , Lymphoma Ocular ... Recurrent and chronic ... #Syndrome #diagnosis ... #management #signs
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... : • Behçet Syndrome ... purpura: strong sign ... differential #diagnosis ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... • Behcet syndrome ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... and leukemia •
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
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