50 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... inhibitor) 2) Osmotic ... diuretics (e.g. ... Metolazone) 5) Potassium-sparing ... #pharmacology #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... • Triamterene OSMOTIC ... DIURETICS • Mannitol ... summary #table #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
the Nephron - Diuretics ... Acetazolamide 2) Osmotic ... Diuretics (e.g. ... HCTZ) 5) Potassium-sparing ... Pathophysiology #Nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Hypernatremia - Differential ... Diagnosis Inadequate ... • Osmotic diuresis ... #Diagnosis #Causes ... #nephrology #sodium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Hyponatremia - Differential ... Diagnosis Algorithm ... and metabolic alkalosis ... , Ketonuria, Osmotic ... #Causes #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
Hypophosphatemia - Differential ... Diagnosis Algorithm ... Acute Respiratory Alkalosis ... Fanconi Syndrome • Osmotic ... Diuresis • Acute
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , Osmotic diuresis ... Hypokalemia #Causes #differential ... #diagnosis #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - Osmotic ... diuretic, Loop ... diuresis - Extrarenal ... Classification #Features #Diagnosis ... Comparison #Table #Nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Piretanide Potassium ... Methazolamide Osmotic ... #Pharmacology #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... • Discontinued diuretic ... #nephrology #low ... #potassium