20 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Electrolyte imbalances are common findings in many diseases. The kidney is a principally responsible organ for
findings in many diseases ... principally responsible organ ... broad range of signs ... presents with signs ... #electrolyte #algorithm
Symptoms and Signs of Hypocalcemia
Muscular: Weakness, fatigue, Spasms, cramps
Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... Tetany, Chvostek sign ... , Trousseau sign ... Dermatologic: ... #Symptoms #Signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... indicated • For organ-specific ... signs or symptoms ... #diagnosis #hematology
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
and associated disorders ... Hyperpigmentation - Hyperkalemia ... Autoimmune thyroid disease ... and associated disorders ... Insufficiency #Signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... of end-organ damage ... including hypokalemia ... renal bruit or signs ... Renal parenchymal disease
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... of end organ damage ... hydration - Hyperkalemia ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... with multiple organ ... the suspected organism
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... or symptoms warranting ... underlying heart disease ... underlying heart disease ... #Evaluation #Algorithm