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hematology management differential microscopy oncology agglutinin aiha algorithm analysis anemias blood chronic cll cold common cvid disease hemeonc hemolysis hodgkins
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Abnormal peripheral smear ... : • Autoimmune ... Hemolytic Anemias ... Hemolytic Anemias
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... or negative - Smear ... #Hemolytic #Anemia ... Pathophysiology #diagnosis ... #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Microspherocytes: Autoimmune ... hemolytic anemia ... #Analysis #hematology ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Membrane): - Autoimmune ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Viral Infection Clinical ... Diagnosis: • hemolytic ... IgM) • Blood smear ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... : Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... hemolytic anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... anemia • Pain ... #classification
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