13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Systemic #Lupus ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... age, however the disease ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... skin injury) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Parkinsons plus syndromes have features of parkinsonism but they differ from parkinsons disease in having some
Parkinsons plus syndromes ... unresponsive to treatments ... #Diagnosis #Neurology ... PSP #LewyBody #MSA ... #Algorithm
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Multiple Sclerosis Treatment ... sclerosis #diagnosis #management ... #neurology #treatment
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... Treatment: Treatment ... demyelination syndrome ... vaptans (HF/liver disease ... #management #nephrology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... MCTD - Bechet disease ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management ... #neurology #differential