12 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Agent Orange or Hep ... C Clinical Presentation ... Diagnosis: • ... • Richter’s Syndrome
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip ... , shoulder ... #differential #diagnosis ... #causes #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Mycoplasma, EBV, HIV ... Test: Donath-Landsteiner ... test #cold #
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Orthopedic Emergencies ... - Remove all ... affected part should ... • Syndrome caused ... tibia/fibula) and hip
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Hematological: - HIT ... • Nephrotic Syndrome ... antibodies (APLS should ... considered in all
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... the critically ill ... tests before beginning ... - Compartment syndrome ... Ethylene glycol - HIV
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
related to dog bites ... the key to the diagnosis ... Capnocytophaga infection should ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... transplantation CLINICAL ... and sensitive tests ... Guillain #Barre #Syndrome
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... auricular papules Clinical ... -74%] • Blood tests ... #rheumatology #dermatology ... #diagnosis