38 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Check plasma osmolality ... mmol/L - true hyponatremia ... • nephrotic syndrome ... renal failure #Hypernatremia
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... 1) Check Urine Osmolality ... Extrarenal Hypernatremia ... Hypervolemic: Conn syndrome ... , Cushing syndrome
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... Calculate serum osmolality ... Measure urine osmolality ... demyelination syndrome ... of symptomatic (seizures
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... urea causes the hyponatremia ... True hyponatremia ... #hyponatremia #ADH
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Hyperglycemia, Hyponatremia ... Eclampsia, Prophyria #Seizures
Causes of Pediatric Seizures - Differential Diagnosis Algorithm
Infantile:
 • Benign Focal Epilepsy of Infancy
 • West
Causes of Pediatric Seizures ... • Dravet Syndrome ... Infection: • Febrile Seizures ... Hypocalcemia • Hyponatremia ... Cataplexy #Seizures
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Hypertonic Saline: seizure ... Overcorrection of Hyponatremia ... Demyelination Syndrome ... MetroHealth_EM #Hyponatremia
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... hypertension, Seizures ... Hepatorenal syndrome ... Hepatoadrenal syndrome ... Hepatopulmonary syndrome
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... vomiting, diarrhea, hyponatremia
Posterior Reversible Encephalopathy Syndrome (PRES) - Diagnosis
Clinical Features:
 • Altered mental status (Either lethargy, confusion, or
Encephalopathy Syndrome ... PRES) - Diagnosis Clinical ... agitation) • Seizures ... Risk Factor + Clinical ... Encephalopathy #Syndrome