6 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Signs and Symptoms ... Proximal limb muscle wasting ... #PBC #cholangitis ... #diagnosis #workup
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... (primary biliary ... cholangitis) overlap ... #symptoms #testing ... #workup
Emergent Causes of Headache and Associated Risk Factors
Carbon monoxide poisoning
 - Breathing in enclosed or confined
Emergent Causes of Headache ... ventilation of heating ... conditions (eg, military ... dormitories) - Lack of primary ... #redflags #signs
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Blast Phase: • Headaches ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... + distinctive primary ... Leukemia #Hematology #Oncology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
may present with headache ... except for the primary ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup