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diagnosis differential hematology algorithm causes cholangitis primary aih arthritis autoimmune chemistry cirrhosis classification common cvid disease disorders enzymes gap globulin
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, PBC, PSC, IgG4 ... function may be abnormal ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... Diagnosis: • Viral hepatitis ... cholangitis #diagnosis #workup ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Alcoholic hepatitis ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology ... transaminitis #LFTs
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
) PSC is a chronic ... to multi-focal biliary ... colorectal and hepato-biliary ... disease management ... #summary #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... gastric bypass), LFT ... not required in all ... #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... - Symptoms of chronic ... reported (eg AIH-PBC ... upper limit of normal ... #Hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... box indicates all ... include extrahepatic biliary ... #LFTs #Abnormal ... #Algorithm #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Presence of CP or PC ... ) • Use of B-cell ... #Indications #management ... #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... disease • Liver ... diseases and hepatitis ... autoimmune hemolytic anemia
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