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diagnosis differential hematology algorithm alp phosphatase biliary cholangitis cirrhosis classification disorders elevation fever gap globulin hepatitis hodgkins hyophosphatasia infectiousdiseases injury
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... biliary Cholangitis (PBC ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... stone, Malignancy, PBC ... (hemolysis, bleeding ... (hemolysis) • ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Labs: • Alkaline ... obstruction • ALP ... cholangitis #diagnosis #workup ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Most cases diagnosed ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... bypass), LFT (liver ... #Workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... anemia Indirect ... from ischemia WBC ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... platelets - WBC
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Thalassemia, Sickle cell anemia
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
infections, a common cause ... aminotransferase and alanine ... No hemolytic anemia ... Investigations: • CBC ... including tests of liver
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