11 results
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... membrane disorder ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... smear, HIV/HCV testing ... changes), high MCV anemia ... #Workup #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
symptoms - most common ... anemia • Cold ... Positive Coombs testing ... Blood smear - RBC ... #anemia #hematology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Spot PC (protein ... LDH - Assess for hemolysis ... infections are common ... causes of glomerular ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Spot PC (protein ... LDH - Assess for hemolysis ... infections are common ... causes of glomerular ... glomerular #disease #workup
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... #oncology #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Most common cytopenia ... Workup: • Complete ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Connective tissue disorders ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia ... Comment on type