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diagnosis hematology management anemia glomerular nephrology agglutinin algorithm blood cellulitis classification cold common cvid dermatology differential glomerulonephritis hodgkins hypogammaglobulinemia immunodeficiency
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... hemorrhage and hemolysis ... intravascular hemolysis ... out an immune hemolytic ... the severity of hemolysis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Positive Coombs testing ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Febrile Non-Hemolytic ... - Acute Hemolytic ... Hemolysis on labs ... - Delayed Hemolytic ... , fever, minor hemolysis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
for glomerular disease ... Spot PC (protein ... LDH - Assess for hemolysis ... infections are common causes ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... Spot PC (protein ... LDH - Assess for hemolysis ... infections are common causes ... #workup #diagnosis
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... Hippocrates in 5 BC ... chronic liver disease ... hemochromatosis, hemolytic ... dermatology #legs #clinical
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... platelets - WBC ... number of sites of disease
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