6 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... granulomatosis: • EBV-associated ... lesions • 80% with lung ... multiple lesions Infectious ... Lesions #Brain #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... Clinical Presentation ... - Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
hemorrhage • CSF PCR ... Toxoplasma gondii PCR ... • JC-virus PCR ... Enhancement • PCR ... #Infections #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... antibody, Anti-GBM ... usually low in anti-GBM ... confirm DAH, r/o infection ... sparing of the lung
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... Pathophysiology: Spore ... non-toxigenic • Stool PCR ... Bezlotoxumab 10 mg/kg
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tenderness → Consider infectious ... Aldolase levels • EMG ... • ANA < 20 % IBM ... #rheumatology #differential