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management infectiousdiseases agglutinin aids algorithm anemia autoimmune causes cdi cdiff clostridioides clostridium cold difficile disease encephalitis gastroenterology gravis hematology hemolytic
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
PCR 50% sensitive ... granulomatosis: • EBV-associated ... RingEnhancing #Lesions #Brain ... #differential # ... #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
hemorrhage • CSF PCR ... Toxoplasma gondii PCR ... • JC-virus PCR ... Enhancement • PCR ... #Infections #differential
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... localized) 1. ... Coxsackie, HIV, CMV, EBV ... #Diagnosis #neurology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Antibodies: 1. ... Donath-Landsteiner Antibodies[PCH ... - Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... Liver Injury: • Infectious ... HBV, HCV, HEV, EBV ... rises later - Half-life ... , RBC, kidney, brain
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... simplex virus 1 ... virus • CMV • EBV ... #Infections #differential ... #diagnosis #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Myotonic dystrophy - Brain ... Miller Fischer and PCB ... precipitated by: Drugs, infection ... #management #neurology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Acute Diarrhea (>3 BM ... Epidemiology: • #1 ... non-toxigenic • Stool PCR ... Bezlotoxumab 10 mg/kg ... IV x 1 - Adjunct
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... varying degrees of: 1. ... Brucellosis - Dengue, EBV ... #management #neurology ... #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Tenderness → Consider infectious ... Ab • Anti-Jo-1 ... • ANA < 20 % IBM ... enzymes • Anti-Jo-1
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