16 results
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... - No other workup ... CBC, aPTT, +/- CXR ... #hematology #diagnosis ... #algorithm #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... - pulmonary opacities ... fluid overload, PCC ... #management #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
AECOPD) Obtain workup ... ventilated • CXR ... doppler, CTA • ECG ... #Exacerbation #treatment ... #pulmonary
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... organ damage • Treatment ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... IgG4+ cells" Treatment ... Glucocorticoids (0.6 mg/kg ... management #phenotypes #workup ... #treatment #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Blood cultures • CXR ... early disease) • CXR ... Clindamycin in case of PCN ... • Vasculitis (e.g ... Lung #Abscess #pulmonary
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... titer, ACE level, CXR ... (to support a diagnosis ... #diagnosis #testing ... #Rheumatology