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differential symptoms erythematosus lupus oncology sle workup algorithm arthritis autoantibodies bleeding child chronic cll dermatology disorders henochschonleinpurpura history hsp igav
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... skin thickening Signs ... pericarditis • Hepatic ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
guidelines General - Systemic ... neurology, back pain Haematology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... Lupusreference #SLE #Systemic ... autoantibodies #signs ... #differential #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
and Arthritis in Pediatrics ... - Differential Diagnosis ... migrans: • Target sign ... Suggestive of systemic ... #peds #pediatrics
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
Diagnosis of IgA ... - Most common systemic ... the skin - Systemic ... #Rheumatology # ... Peds #Pediatrics
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... ’s CLL Scoring system ... Neutropenia, anemia, thrombocytopenia ... workup #oncology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... syndrome - IGG4 - Hepatic ... in LNs and the systemic ... Histopathological Diagnoses ... #management #rheumatology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
• Presence of systemic ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
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