11 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... Tuberculosis Diagnosis ... staining, NAA (PCR ... Tuberculosis #TB #Diagnosis ... #ActiveTB #LatentTB
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... Tuberculosis Diagnosis ... staining, NAA (PCR ... Tuberculosis #TB #Diagnosis ... #ActiveTB #LatentTB
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
ANTIBIOTICS WITH ... Class Overview ... Combined PCN/Beta-Lactamase ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... other agents are: activity ... choice, both for treatment ... #Pharmacology #Antibiotics
Clindamycin - Antibiotics Class Overview
-50 S inhibitor (PO and IV)
Spectrum: Excellent activity vs. Anaerobes and Gram
Clindamycin - Antibiotics ... Class Overview ... Also has activity ... vs PCP (combine ... pyrimethamine) #Pharmacology
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
Class Overview ... Legionella), also some activity ... Strep throat in PCN ... Used for MAC treatment ... #Pharmacology #Antibiotics
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... Spectrum: only has activity ... cross-reactivity with PCN ... #Pharmacology #Antibiotics ... #Review #Overview
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Class Overview ... Ertapenem has no activity ... so use only if PCN-allergic ... empiric Pseudomonas treatment ... Polymyxin B(IV) #Pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... of a previously diagnosed ... No specific diagnostic ... leukoencephalopathy (PML ... • Persistently active
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Overview ... Sjogren's Syndrome Diagnosis ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... muscarinic agonists • Active