17 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... #neurology #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
WAIHA • CAD • PCH ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Clinical Features ... and CNS • Headache
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Autoimmune diseases • Clinical ... symptoms - Pel-Ebstein ... Differential Diagnosis ... #oncology #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... fluid overload, PCC ... #management #hematology ... #oncology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... antibodies (aPL): • Lupus ... at least: • 1 clinical ... presence of 1 clinical ... to be present Treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... basal ganglia, CNS ... (Clinical Dx). ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology