12 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... female, asian • Systemic ... specific laboratory tests ... #Related #Disease ... #phenotypes #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... Quantitative IgA, IgG ... #Causes #Workup ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... symptoms - Pel-Ebstein ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... should be obtained ... immunoglobulin G (IgG ... #diagnosis #testing
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... anemia due to cold IgG ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hemoglobinuria (PCH ... Donath-Landsteiner (IgG ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... adults in the west ... cells can indicate disease ... #workup #oncology ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
- ANA > 95% (IgG ... months to years) Systemic ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Diagnosis ... Tuberculin skin test ... staining, NAA (PCR ... HIV-infected patients should ... Tuberculosis #TB #Diagnosis
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
treatment Nephrogenic Systemic ... patches on back, shoulder ... paraproteinemia (IgGλ ... #comparison #table ... #dermatology