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Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders - Differential ... • Metabolic Acidosis ... • Respiratory Acidosis ... (pCO2 > 40 mmHg ... Diagnosis #Algorithm #Causes
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Differentials? ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... Step 5 - Differential ... Base #Gas #VBG #differential
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
+ Respiratory Acidosis ... Alkalosis pH ↓ pCO2 ... pH ↑ pCO2 ↑ - ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2 ... , pCO2) move in ... Nephro #AcidBase #Acidosis
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... Respiratory Acidosis ... Medications, Central, ↑ CO2 ... gap metabolic acidosis
Acid Base Disorders Worksheet Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
has a primary acidosis ... >40 patient's acidosis ... <40 patient's acidosis ... diagnoses using the differentials ... Worksheet #diagnosis #differential
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... (Patm - 47) - (PaCO2 ... Level) [150- (PaCO2 ... Hypoxia #hypoxemia #differential
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
Evaluation and Differential ... are they more acidotic ... and ~5 mmHg to pCO2 ... Differential Diagnosis ... Evaluation #workup #Differential
Blood Gas (ABG) Interpretation and Acid-Base Pathology 1- Does the patient have an acidosis or an alkalosis?
patient have an acidosis ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... is a metabolic acidosis
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
type of hypoxia) PIO2 ... O2 is inspired) PAO2 ... Low SvO2 → Low PaO2 ... summary #pulmonary #differential ... #diagnosis #causes
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