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Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders - Differential ... Diagnosis Algorithm ... • Metabolic Acidosis ... • Respiratory Acidosis ... #Diagnosis #Algorithm
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... Respiratory Acidosis ... Medications, Central, ↑ CO2 ... acidbase #workup #algorithm
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -
+ Respiratory Acidosis ... Alkalosis pH ↓ pCO2 ... pH ↑ pCO2 ↑ - ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2 ... , pCO2) move in ... Nephro #AcidBase #Acidosis
Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
has a primary acidosis ... >40 patient's acidosis ... <40 patient's acidosis ... diagnoses using the differentials ... Worksheet #diagnosis #differential
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... Step 5 - Differential ... Base #Gas #VBG #differential
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... (Patm - 47) - (PaCO2 ... Level) [150- (PaCO2 ... Hypoxia #hypoxemia #differential
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Evaluation and Differential ... are they more acidotic ... and ~5 mmHg to pCO2 ... Differential Diagnosis ... Evaluation #workup #Differential
Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?
patient have an acidosis ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... is a metabolic acidosis
Blood Gas Analysis and Interpretation
STEPS TO ANALYSIS
1. Look at PH. Alkalotic or acidotic?
Alkalotic or acidotic ... - If acidotic ... then it is an acidosis ... - pCO2 (respiratory ... - alkalotic or acidotic