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Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
- Differential Diagnosis ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... #Differential #Diagnosis ... #Algorithm #Causes
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2 ... , pCO2) move in ... #Diagnosis #Nephro
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... (Patm - 47) - (PaCO2 ... Level) [150- (PaCO2 ... #differential #diagnosis
Capnography Measurement of exhaled carbon dioxide can be used to confirm ETT placement, for safer procedural sedation,
- Alveolar CO2 ... • PvCO2 - Mixed ... venous CO2 • ... PaCO2 - Arterial ... waveforms #patterns #diagnosis
ABG vs VBG: Arterial vs Venous Blood Gases ABG PROS: Tells you exactly what the arterial environment looks
vs Venous Blood Gases ... looks like (pH, PaCO2 ... Comparison #pH #pCO2 ... #Diagnosis #Differences
What's in a Blood Gas? VBG vs ABG BOTTOM LINE: VBG is less painful, more easily obtained
very well, and PvCO2 ... #EBM #Diagnosis ... Comparison #PH #PCO2
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
type of hypoxia) PIO2 ... O2 is inspired) PAO2 ... Low SvO2 → Low PaO2 ... #differential #diagnosis ... #causes #pathophysiology
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase #Diagnosis
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... Medications, Central, ↑ CO2 ... workup #algorithm #diagnosis
Acid Base Disorders Worksheet Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
CI-, HCO3-, PH, pCO2 ... 3: Look at the pCO2 ... . 3a: If pCO2 ... Step 7: Make the diagnoses ... Disorders #Worksheet #diagnosis
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